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Tryptophan metabolites can activate the aryl hydrocarbon receptor (AhR), modulating immune responses to favor cardiovascular homeostasis [42]

Recommended reading Alissou M, et al

Rosenkilde, MM (July 2021) 'The role of incretins on insulin function and glucose homeostasis', Endocrinology , 162/7, bqab065

[DOI] [PubMed] [Google Scholar] Krystal JH, Karper LP, Seibyl JP, Freeman GK, Delaney R, Bremner JD, Heninger GR, Bowers MB, Jr., Charney DS

Researchers can use it to generate clean concentrationresponse relationships, evaluate second-messenger readouts such as cAMP in GLP-1 and GIP pathways, or examine glucagon-receptor engagement under predefined assay conditions