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Crosstalk among these pathways maintained by glutathione-dependent redox balance enables cancer cells to withstand oxidative and metabolic stress, thereby driving tumor progression

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Ahrn B, Holst JJ, Mrtensson H, Balkan B

This has led to multi-hormonal agents that act simultaneously on glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), glucagon, amylin and/or peptide YY (PYY), better replicating the physiological and coordinated post-prandial response

GLP-1s can cost as much as $1,000 per patient per month, fueling a 11-12% rise in prescription drug expenses and comprising over 18% of total plan spend