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Laboratory studies suggest the peptide can shift gene-expression patterns toward a profile associated with younger tissue and may support the activity of cells involved in repair

A cohort study of moderate and severe head injury patients found that 67% of the cerebrolysin group achieved good outcomes (GOS 3-5) at 6 months, compared favorably to historical controls matched for age, sex, and initial severity

ACCEPTED MANUSCRIPT ARTICLE IN PRESS ARTICLE IN PRESS Biochemical Analysis Serum malondialdehyde (MDA), an index of lipid peroxidation, was quantified using a rat-specific ELISA kit (Sunred Biological Technology, Shanghai, China) and expressed as nmol/mL

Its considered one of the most important antioxidants in the human body (5)

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