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We ranked the models by their predicted local distance different test (pLDDT) and selected the top two models of different linker lengths (20 and 30 amino acids) to test experimentally

discovered that elevated serum TMAO levels in HD patients raise carotid-femoral pulse wave conduction velocity (cfPWV), thereby increasing aortic stiffness and the risk of cardiovascular disease (Shafi et al., 2017

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Meanwhile, Novo has launched a new late-stage trial for its experimental next-generation obesity drug candidate, CagriSema (cagrilintide/semaglutide)