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Avoid injecting two medications in the exact same spot

The combined effects lead to improved glycemic control in people with type 2 diabetes and substantial weight loss in appropriate patients

The trade-off: tirzepatide costs about $50$100/month more than compounded semaglutide

Trial Status: Active, not recruiting Clinical Trials Identifier: NCT05536804 Trial Name: Tirzepatide Study of Renal Function in People With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes: Focus on Kidney Hypoxia in Relation to Fatty Kidney Disease Using Multiparametric Magnetic Resonance Imaging (TREASURE-CKD) Diabetes Type: With or without type 2 diabetes Trial Sponsor: Eli Lilly and Company What is the aim of the study

The retatrutide dose schedule still recommends starting at a conservative dose to assess tolerance of the glucagon component, even if you were on high-dose tirzepatide previously