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The ROS generated from aerobic respiration caused a cumulative oxidative damage in macromolecules, including lipids, DNA, and proteins, which subsequently lead to cells death (Scheibye-Knudsen et al., 2015), and affect the healthspan of numerous principal organ systems (Dai et al., 2014)

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Copper complexes can be sensitive to Light exposure Moisture and humidity Elevated temperatures and temperature cycling Repeated freeze thaw cycles when in solution If these are not controlled, the actual material in the vial can change over time

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