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While Big Tobacco companies like Philip Morris International claim to be working towards a smoke-free world and transitioning away from cigarettes, they spent over $8.4 billion in 2018 alone marketing and promoting conventional combustible cigarettes

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Regarding the long-term effects of e-cigarette smoking on cardiac autonomic tone, a cross-sectional study comparing cases (e-cigarette users) and controls (healthy individuals with no history of smoking) who had used nicotine-containing e-cigarettes on most days for at least 1 year, showed a significant increase in sympathetic activity compared to the control group (30)

As per WHO, 12% of the worlds smoking population lives in India