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With diabetes and CKD projected to be the seventh and fifth leading cause of premature mortality worldwide by 2040, respectively [7], novel and effective treatment options are critical

Both are approved by the FDA for weight loss in adults with obesity or overweight plus a weight-related condition

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This is called fragmentation

Modifications and impacts of the gut microbiota and its metabolites in the UC Increasing evidence indicates that UC onset is closely associated with abnormalities in the gut microbiota and its metabolites