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Decreasing overall body fat can lead to improved metabolic health, including better blood pressure, cholesterol levels, and blood sugar control

Taking certain medicines for a long time, like proton pump inhibitors or metformin, can block B12 absorption

The 2026 edition of ICD-10-CM E50.1 became effective on October 1, 2025

Vitamin B12 does require the initial loading dose period, especially in very deficient cats, so improvements will not be immediate