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These biomarkers can serve as non-invasive indicators of mitochondrial dysfunction [33], allowing for the timely identification of individuals at risk of developing cardiovascular diseases and cognitive impairment

Smirnova GV, Oktyabrsky ON

The peptide's efficacy against high-SASP senescent cells proves particularly valuable in the kidney microenvironment, where inflammatory signaling from senescent tubular cells impairs filtration and promotes fibrosis

That convergence of independent findings across diverse research groups adds weight to the overall body of evidence in a way that designed peptides with narrower mechanistic rationales cannot replicate

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