Semaglutide can activate your brains GLP-1 receptors, reducing the feeling of hunger and helping you decrease food intake
For most people these ease off after the first few months
Rare cases of allergic skin reactions have been reported with GLP-1 use, including urticaria (hives), rash, and pruritus (itching)
We describe one such approach, albumin binding, and explain how it was applied in the development of the human GLP-1 analog liraglutide once daily and, subsequently, semaglutide once weekly
In addition to effects on weight and blood glucose control, early laboratory studies in mice suggest that GLP-1 RAs might work through additional biological mechanisms ( 10 , 11 )