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GLP1/E therapy also elicited specific changes in the hypothalamic proteomic profile in PNA mice, upregulating proteins involved in the metabolism of non-coding RNA, signaling of nuclear receptor and estrogen-dependent gene expression and downregulating pathways involved in apoptosis, signaling by insulin receptor and cellular responses to starvation

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The G protein alpha subunit has a key role in determining the specificity of coupling to, but not the activation of, G protein-gated inwardly rectifying K(+) channels

Under ADR treatment, MCF-7/ADR cells showed a higher autophagy level than MCF-7 cells