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Because B12 is water-soluble, your body uses what it needs and passes most of the excess, and there is no established upper intake limit because harmful effects from high intake have not been well documented

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Dr Sudhir Kumar MD DM (@hyderabaddoctor) January 23, 2023 As such, we reached out to experts to understand the role of vitamin B12, its deficiency, and whether it is possible to overdose on supplements or injections

Dose can be increased in 2.5 mg increments every four weeks to a maximum of 15 mg weekly