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The reduction in the concentration of GSH in yeasts might have resulted in the consumption of selenium in reactions with free radicals, which are produced in excessive amounts, which was accompanied by an increase in the concentration of the oxidized form of glutathione (GSSG)

Moreover, the increase in GSH levels induced by Nrf2 activation prevents the p75 NTR -mediated apoptosis of neurons in vitro ( In our mouse model, BSO and iAs up-regulated NGF protein levels in plasma although in the case of iAs, at a delayed time scale (Figure 1) that was not associated with TrkA activation in the striatum (Figure 3)

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Creatine has been shown to reduce muscle fatigue by increasing muscle energy during exercise (Smith-Ryan et al., 2021)