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The body adjusts glucagon receptor sensitivity, autonomic balance shifts, and the cardiovascular system reaches a new equilibrium

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Abstract Aims/hypothesis Whether sodiumglucose co-transporter 2 inhibitors (SGLT2is) or glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are cost-effective based solely on their cardiovascular and kidney benefits is unknown

December 3, 2025