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The side effects were most commonly gastrointestinal disturbances such as nausea and vomiting and occurred in a similar frequency to those reported with dual receptor co-agonists [61]

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After cell death, the capsule ruptures, and the contents are released into the tissue, activating the surrounding immune cells that then promote inflammation (Tonnus et al., 2018)

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At the same time, these vessels function as conduits that facilitate continual infiltration of immune cells and inflammatory mediators, creating a self-reinforcing cycle of inflammation and angiogenesis

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