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Description

J Pharmac Invest

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Rapamycin, a pharmacological inhibitor of the mechanistic target of rapamycin (mTOR), activates autophagy/mitophagy in a PINK1/Parkin-dependent manner [313]

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It is commonly prescribed off-label for weight loss at doses up to 2mg weekly

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doi:10.1038/ejcn.2011.59 Safer choice

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doi: 10.1016/j.celrep.2014.10.032 68 GrassetEPuelACharpentierJColletXChristensenJETercFet al

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