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These are gaps in the research record, not established safety findings

doi:10.1042/BST0330811

Possible B12 injection side effects tend to be mild and short-lived, and may include: Injection site pain, redness, or swelling Mild itching Brief diarrhea (less common) A feeling of warmth after the injection Serious side effects are rare

Potential side effects, though rare, can include allergic reactions to the injected substances, infection at the injection site, and minor bleeding or bruising

They are often sufficient for correcting mild dietary deficiencies (e.g., in vegans who dont consume fortified foods) and can sometimes be used for maintaining levels after an initial course of injections, provided absorption is adequately monitored by a healthcare professional