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The fall in electron potential energy through this electron transport chain (ETC) is used to pump protons out the mitochondrial matrix to the intermembrane space (IMS)

Short-acting anticholinergics like Ipratropium bromide (Atrovent) help in blocking, for short periods, the action of acetylcholine, but long-acting anticholinergics (LAMAs), a recommended treatment mainstay, sustain the relief and are used for maintenance therapy

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