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DOI: Preclinical studies across rodent and primate models have documented dose-dependent GH secretion with published doses typically in the range of 12 g/kg IV

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The article calls the clinical outcome unpredictable: some patients experience blunted semaglutide efficacy, while others see improved glycemic control because semaglutide's insulin-enhancing properties offset prednisone's hyperglycemic effect

GLP-1 injections can cause short-term gastrointestinal side effects and may trigger nausea and vomiting, diarrhea or constipation, bloating and stomach discomfort, fatigue, dizziness, headaches and injection-site redness or itching