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Then, 10 l of equilibrated anti-FLAG (M2) agarose was added to the mixture, which was then incubated for 60 min at room temperature

Otic agents and/or other pharmaceutical agents disclosed herein are optionally incorporated within controlled release particles, lipid complexes, liposomes, nanoparticles, microspheres, nanocapsules or other agents which enhance or facilitate the localized delivery of the otic agent