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71.2 lbs on average) Retatrutide 9mg: 26.4% body weight reduction Tirzepatide/Zepbound (Phase 3 comparison, not head-to-head): ~20.9% Semaglutide/Wegovy (Phase 3 comparison, not head-to-head): ~14.9% Placebo: ~2.1% Note: These figures come from separate Phase 3 trials and are not direct head-to-head comparisons

doi: 10.3945/ajcn.110.003483

Besides Cagrilintide, there are other insulin-based molecules in early clinical trial phases, including long-acting insulin agonists and a dual receptor agonist that binds both insulin and calcitonin activities

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Regular monitoring helps ensure the frequency remains appropriate Once levels stabilise, injections are usually spaced further apart, often every few months