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Investigation Areas Multi-peptide co-formulation screening and excipient compatibility In-vitro stability (pH/temperature/light) and oxidative stress challenges Solubility/vehicle selection and filtration method development Analytical method development for multi-analyte matrices Packaging/closure interaction and adsorption studies Handling Requirements Use calibrated balance and sterile technique where applicable Document solvent, concentration, and reconstitution date Minimize moisture/air exposure

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doi: 10.1210/jcem.74.4.1532179 36 WiersingaWM