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"With a reaffirmed safety and tolerability profile, we strongly believe in its potential to help even more people with obesity reach their individual weight loss as well as their broader health goals, including improvements in cardiovascular and kidney health, liver disease, type 2 diabetes, and mobility through knee osteoarthritis pain reduction." Photo by Haberdoedas on Unsplash
It takes about 5 weeks to reach a maintenance dose with liraglutide, but it can take 17 weeks to reach a maintenance dose with semaglutide
However, recent approaches that pair xanomeline with trospium, a peripherally acting muscarinic antagonist, have improved tolerability and clinical efficacy, leading to regulatory approval [225, 226]
Efficacy of semaglutide in treating obesity: a systematic review of randomized controlled trials (RCTs)