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Most study referrals came from the Michael J Fox Foundation Trial Finder (45%) and Washington State PD Registry (42%), with health-care providers and friends contributing to the remaining referrals (13%)

Do not adjust dosing based on online charts or social media

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The progression of DN can lead to severe consequences, including pain, loss of sensation, and increased risk of foot ulcers and amputations, which collectively strain global healthcare resources ( The clinical manifestations of DN can vary widely, ranging from asymptomatic cases to severe pain and functional impairment