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Researchers often evaluate identity, purity, storage conditions, concentration format, route-format comparisons, related compounds, and batch documentation before selecting a material for controlled laboratory use

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Nature 500 (7464), 541546

A prolonged, untreated deficiency can cause nerve damage that may become permanent

Table 6: Treatment of folate deficiency (adapted from Means 2021) 27 TOP Ongoing Care Ongoing Management Vitamin B 12 Duration of therapy Once a diagnosis of B 12 deficiency due to poor absorption of B 12 has been made, therapy should be maintained lifelong