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Following the recommended slow dose titration protocol and implementing dietary modifications substantially reduces the incidence and severity of gastrointestinal side effects

The formation, length control, and function of cilia rely on intraflagellar transport (IFT), a bidirectional protein transport system coordinated by three large protein complexes, IFT-B, IFT-A, and BBSome, with molecular motors along the ciliary axonemal microtubules

Briefly, mice were dark-adapted overnight and then anesthetized with an intraperitoneal injection of 100 mg/kg ketamine and 10 mg/kg xylazine diluted in saline (Otsuka)

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