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Glucagon-like peptide-2 ameliorates age-associated bone loss and gut barrier dysfunction in senescence-accelerated mouse prone 6 mice

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A trial conducted for 12 weeks on 30 subjects with a treatment of once-weekly semaglutide dose up to 1 mg indicated a change in weight of an average of 5.0 kg loss of weight which may be attributed to decreased energy intake and appetite (a total of 24% reduction in energy across all meals consumed) in individuals on semaglutide vs placebo

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