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To elucidate the transcriptional program associated with GLA-mutant kidney organoids and the consequences, 100 differentially expressed genes (DEGs) were first identified on the basis of fold change values (50 genes were upregulated and downregulated in GLA-mutant Fabry kidney organoids compared with WT kidney organoids

Preparation of stock solution of n-acetyl l-cysteine 10 mg of n-acetyl l-cysteine was accurately weighed, transferred into a 10-ml volumetric flask and dissolved using a small amount of 0.1 N KOH, and then, the volume was made up using distilled water

Pearson correlation coefficient r = 0.85, Markov Clustering Algorithm = 1.7