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It also stimulated migration and proliferation of cells at and near the injury sites by almost three-fold

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Glutathione (GSH) is a vital intracellular antioxidant that protects cells from oxidative damage, particularly relevant to diabetes where GSH depletion is implicated in insulin resistance and -cell dysfunction (Figure 2)

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Several ongoing clinical trials are combining these glutamine-altering drugs with immune checkpoint inhibitors or with inhibitors of receptor tyrosine kinase signaling, the major signal that tells cells to acquire nutrients and grow