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This is the second group of warning letters sent since a September crackdown on misleading direct-to-consumer pharmaceutical advertisements was launched following US President Donald Trumps order for tighter oversight of how companies promote prescription drugs

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While numerous randomized clinical trials substantiate the antidepressant efficacy of Rhodiola, Ginkgo, and Ashwagandha, these investigations are frequently hindered by limited sample sizes, diverse dosing protocols, variability in extract standardization, and insufficient integration of mechanistic biomarkers

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