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On the one hand, sarcopenia is significantly associated with an increased risk of MASLD (106), and in patients with MASLD, sarcopenia is associated with an increased risk of liver fibrosis, independent of obesity or insulin resistance (107)

The fetal mortality was not clearly indicative of any marked toxic effects other than those involving the dam, since whole litters were not involved

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While these findings suggest potential utility for early detection and risk stratification, multicenter validation and longitudinal follow-up are needed to confirm that alterations in carnitine levels precede eGFR decline and are not merely a consequence of impaired renal clearance

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