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Phosphorylation can weaken the ankyrinBand 3 interaction, destabilizing the cytoskeleton and impairing erythrocyte mechanical properties ( In human erythrocyte membranes, PTPs are positioned near Band 3 and generally show high activity to prevent excessive tyrosine phosphorylation

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

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