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Int J Mol Sci 17:190

Absorption and Availability A B12 deficiency can result from a lack of intrinsic factor, a substance needed to absorb B12

Some facilities use both approaches together for difficult wounds, though research on combined protocols is limited

Its main actions include: Stimulating insulin secretion from pancreatic beta cells in a glucose-dependent manner Suppressing glucagon release, which reduces hepatic glucose production Slowing gastric emptying, which moderates post-meal glucose spikes Promoting satiety through central nervous system pathways, thereby reducing appetite GIP is released by K-cells in the proximal small intestine and shares some functions with GLP-1, particularly in enhancing insulin secretion after meals