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(2) Tkalcevi VI, Cuzi S, Brajsa K, Mildner B, Bokuli A, Situm K, Perovi D, Glojnari I, Parnham MJ

Our experience shows that researchers often begin with a lower concentration, such as 1-2 M, and then gradually increase it to observe dose-dependent effects

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What has been reported in the available human pilot research is that no significant adverse effects were observed - which is a meaningful data point for safety consideration, even if it does not establish efficacy by clinical standards