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A 2012 meta-analysis showed that older adults who had received the zoster vaccine had a 50% reduced incidence of shingles compared with those who had a placebo vaccination

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The integrity of transcriptional programming related to the epidermal barrier from reactive and non-reactive patients was further confirmed using single-cell transcriptomic data, indicating programmes encoding tight junctions, desquamation, keratinisation, cornification, lipid metabolism and desmosomes were not compromised in the skin of reactive patients (Supplementary Fig

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