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Negative Effects of Weed Along with common adverse reactions to cannabis, like abnormal heart rate, dizziness, altered thinking, hallucinations, appetite changes, low blood pressure, bad mood, panic attacks, etc., in some cases we observe such gastrointestinal side effects as: Repeated vomiting and diarrhea Nausea Constipation Abdominal cramps Tender and painful stomach Slow gastric motility, which is associated with unpleasant and painful sensations in the stomach These issues usually happen only after daily heavy weed use for many years

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