Eli Lilly's retatrutide may be the first real test of whether healthcare boards are prepared for multi-indication valueand the governance frameworks it demands
This hands-on approach allows him to identify how each patients body is responding and make timely adjustments to dosage or lifestyle recommendations when needed
SAN DIEGO-Bariatric surgery far outperforms lifestyle interventions and glucagon-like peptide-1 (GLP-1) medications at maintaining weight loss, according to a meta-analysis presented at the 2024 annual meeting of the American Society for Metabolic and Bariatric Surgery
These benefits make the process feel rewarding even before major weight loss is achieved
For GLP-1 users specifically, I prioritize movements that protect the muscle groups most vulnerable to atrophy during rapid weight loss: Lower body: Squats ( meaning any form of knee bend), deadlifts, lunges (glutes, quads, and hamstrings are the largest muscle groups and the biggest contributors to metabolic rate) Upper back and lats: Rows, pulldowns (postural muscles that deteriorate quickly without stimulus) Chest and shoulders: Presses, overhead work, flyes (functional pushing strength) Core: Planks, Pallof presses, loaded carries (spinal stability, injury prevention) Safety Note: If nausea is severe during early titration, reduce training volume (fewer sets per exercise) rather than eliminating sessions