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Parkinson's disease (PD) PD is the second most common neurodegenerative disease following AD, and is associated with the loss of dopaminergic neurons in the Substantia Nigra compacta (SNc)

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The above led us to test a blend of taurine, vitamin B6, B9, and B12 in humans, in a randomized, double-blind, 2-arm, cross-over study with 44 participants aged 2540 years old

To maintain iron homeostasis, cells employ intricate regulatory mechanisms, including iron uptake via the transferrin receptor (TFR1), storage of iron in ferritin, and ferritinophagy to mitigate the toxic effects of iron overload ( In addition to these well-characterized mechanisms, recent studies have highlighted alternative ferroptosis surveillance pathways that operate independently of GPX4