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The SPR results showed that the K D values of RGD, a classical peptide ligand that binds to the ectodomain of integrin, and ITP2, which binds to bEnd.3 vesicles expressing integrin v 3 , were 17.10 M and 9.66 M, respectively

These findings suggest that survodutide has the potential to reduce liver fibrosis and improve liver function in patients with NASH, making it a promising therapeutic option for this complex liver disease [89]

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The results were not subjective assessments but machine-measured dermal changes