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If you are concerned about acne whilst taking B12 supplements, it is advisable to discuss this with your GP rather than discontinuing treatment without medical guidance, particularly if the B12 has been prescribed to address a documented deficiency

Unlike semaglutide, tirzepatide targets both GLP-1 and GIP (gastric inhibitory polypeptide) receptors, enhancing fat metabolism and insulin sensitivity

Because of these properties, B vitamins have been documented to promote fat gain

That second pathway explains why prolonged deficiency causes neurological damage and not simply anaemia

Beware that cooking and processing may reduce thiamine levels in food