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The US Food and Drug Administration approved the peptide for the treatment of types 1 and 2 diabetes in 2005

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We next investigated whether mitochondria are the source of ROS generation in RPE cells upon GSH depletion, we used MitoSOX Red to detect mitochondrial ROS (Fig

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BPC-157 & Wound Healing Skin, Burns, Diabetic Ulcers & Fistulas (PMC, 2021) A comprehensive wound healing review published in Frontiers in Pharmacology documented BPC-157s practical applicability across skin wound types incisional, excisional, deep burns, diabetic ulcers, alkali burns, and fistula healing confirming equivalent efficacy regardless of route of application (systemic or local) and across the same dose range