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The medication can activate GLP-1 and GIP receptors in circumventricular organsspecialized brain regions including the area postrema and median eminence that lack a complete blood-brain barrier

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Managing Diarrhea While Taking Tirzepatide Stay hydrated throughout the day, as diarrhea increases fluid loss

Best noted that doctors could also recommend other GLP-1 drugs such as liraglutide (Victoza, Saxenda) or even explore weight loss drugs that work through different mechanisms like phentermine, bupropion, or naltrexone

As a small-molecule drug, orforglipron is cheaper and simpler to manufacture than peptide-based drugs such as semaglutide