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28 Fourth, while this study provides insight into GPR15-associated modulation of T-cell populations, the precise molecular mechanisms underlying GPR15-dependent immune regulation remain incompletely understood, especially regarding its effects on Treg-to-Th1 differentiation and Th17 cell stability in the context of cigarette smoke exposure, warranting further investigation

Suction: The act of smoking creates suction in the mouth, which can dislodge the blood clot crucial for healing

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Regulation of endogenous gene expression in human non-small cell lung cancer cells by estrogen receptor ligands