men before and after tirzepatide Zepbound, a drug with the main active ingredient tirzepatide, was found to be more helpful in helping people lose weight than Wegovy, according to new data Zepbound before & after! 🔥

The panel below is his CGM 6 months after taking Tirzepatide 5 mg, without a major change in his diet or lifestyle during which time his weight dropped 7 Kg and his HbA1C dropped from a prediabetic value of 44 to 34 mmol/mol

We see tremendous pressure on the government to change this after the SELECT trials demonstration that the drugs benefits extend to meaningfully reducing cardiovascular disease and deaths

The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats

Unsurprisingly, we found that the putative oxyanion hole, formed by the NH backbone of V12, could be provided by other amino acid residues

Acknowledgements The idea for this Review was developed during a Travelling Fellowship sponsored by the ON Foundation and the International Cartilage Regeneration & Joint Preservation Society (ICRS)