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Continued treatment with GLP-1 RAs plateaued at 22.5% with tirzepatide and 9.714.9% with semaglutide after 1718 months

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137 , 1586S1590S (2007)

Novo Nordisk reined in its growth forecasts for the year in its second-quarter financial results update, blaming "persistent use of compounded GLP-1s, slower-than-expected market expansion, and competition." Compounding of semaglutide should have come to a halt in the US since the drug was removed from the FDA list of medicines in short supply, but various companies continue to provide compounded GLP-1s under a loophole that allows the sale of 'personalised' formulations