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There may to be biological/genetic differences in the cerebral response to ischemia in cardioembolic stroke compared with large artery atherosclerosis

Specific abnormalities include high levels of tissue factor, factor VIII, fibrinogen, and inhibitor of plasminogen activator type 1 activity (148)

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The American College of Obstetricians and Gynecologists (ACOG) has stated that compounded bioidentical hormones carry the same risks as conventional hormone therapy and lack the standardized dosing and safety data of FDA-approved alternatives [11]