These therapies aim to enhance WL and improve metabolic outcomes by engaging multiple hormonal pathways, with preclinical and early-phase clinical trials supporting their potential as next-generation obesity treatments [16,17,18,19,20,21,22,23]
Expression of mouse sialic acid on gangliosides of a human glioma grown as a xenograft in SCID mice
observed that vitamin E could reverse drug resistance in vitro as well as in vivo [262]
(2022), who developed a rapid and sensitive method for analyzing alpha-tocopherol and its oxidative products using supercritical fluid extraction-supercritical fluid chromatography (SFE/SFC) coupled with proton transfer reaction ionization mass spectrometry (PTR-MS), enabling the separation and detection of alpha-tocopherol and its oxidation products, such as the alpha-tocopheroxyl radical and alpha-tocopheryl quinone, in approximately 3 min per sample with high sensitivity and resolution, even for isomers, without extensive sample preparation-a substantial improvement over traditional chromatographic methods that often involve complex processing and long separation times