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Two years after albiglutide (Tanzeum), approval of a FIX albumin fusion, albutrepenonacog alfa (Idelvion), for treatment of hemophilia B, followed 80

2020 Sep;24(8):1471-1483

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While the study establishes a compelling systemic role for SLC25A45 in fuel switching, important questions remain regarding the tissue-specific contributions of this pathway and how carnitine biosynthesis and utilization are differentially regulated across dietary, disease, and sexually dimorphic contexts