Tirzepatide works by reducing hunger signals and slowing gastric emptying, which naturally leads to calorie reduction and body weight loss
For further reading on tirzepatide, its evolution, clinical development, and outcomes, see link:
Eli Lilly, the company that manufactures Zepbound, reported that hair loss was more often seen in female patients and that it was linked to weight loss, meaning it is not that tirzepatide directly attacks the hair follicles but how fast the individual loses weight
For instance, obesity is linked to increased inflammation and possibly a less healthy gut microbiome
Niacinamide formulations may be more relevant for skin, and nutritional interventions including biotin and zinc address hair loss more directly